منابع مشابه
Procedures in Nucleic Acid Research
The rapid development of nucleic acid research has resulted in the emergence of a wide variety of techniques associated with such research. The documentation of even some of these techniques in a well-written form is a formidable task. That the editors of this book have succeeded in producing such a fine first volume is a measure of the care they have taken and the calibre of the specialists co...
متن کاملEditorial: Nucleic Acids Research and Nucleic Acid Therapeutics
1Division of Basic Sciences, Fred Hutchinson Cancer Research Center, 1100 Fairview Ave. N., Seattle, WA 98109, USA, 2RNA Therapeutics Institute, University of Massachusetts Medical School, 368 Plantation Street, Worcester, MA 01605, USA, 3Departments of Pharmacology & Biochemistry, University of Texas Southwestern Medical Center, 6001 Forest Park Road, Dallas, TX 75390-9041, USA, 4Departments o...
متن کاملAdvances in Nucleic Acid Detection and Quantification
The last decade has seen many changes in molecular biology at the bench, as we have moved away from a primary goal of cataloguing genes andmRNA towards techniques that detect and quantify nucleic acid molecules even within single cells. With the invention of the polymerase chain reaction (PCR), a nucleic acid sequence could now be amplified to generate a large number of identical copies, and th...
متن کاملFluorescent hybridization probes for nucleic acid detection.
Due to their high sensitivity and selectivity, minimum interference with living biological systems, and ease of design and synthesis, fluorescent hybridization probes have been widely used to detect nucleic acids both in vivo and in vitro. Molecular beacons (MBs) and binary probes (BPs) are two very important hybridization probes that are designed based on well-established photophysical princip...
متن کاملNucleic acid detection with CRISPR-Cas13a/C2c2.
Rapid, inexpensive, and sensitive nucleic acid detection may aid point-of-care pathogen detection, genotyping, and disease monitoring. The RNA-guided, RNA-targeting clustered regularly interspaced short palindromic repeats (CRISPR) effector Cas13a (previously known as C2c2) exhibits a "collateral effect" of promiscuous ribonuclease activity upon target recognition. We combine the collateral eff...
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ژورنال
عنوان ژورنال: Electroanalysis
سال: 1996
ISSN: 1040-0397,1521-4109
DOI: 10.1002/elan.1140080102